Someone posed the question recently about how Run BASIC http://www.runbasic.com will stack up against Ruby on Rails. I think the question was meant primarily about performance. This is really an apples to oranges comparison because Run BASIC isn't meant to be a scripting language.
While I don't doubt that some people will use Run BASIC to create commercial sites, this is not the focus we are pursuing. Instead we are creating a tool for the traditional users of BASIC. If you want to learn or teach programming, if you want to create web apps for your use at home (or on your iPhone!), or if you need a custom application at the office and the IT folks and programmers are too busy to build it for you then Run BASIC is designed for you. :-)
Coming back to performance, the processing of large web applications is bottlenecked at the database. A Run BASIC front end to a database will perform similarly to other languages like Perl, Ruby, etc.